Structural Brain Abnormalities as Indicators of Vulnerability to Schizophrenia
نویسندگان
چکیده
منابع مشابه
Structural and Functional Brain Abnormalities in Schizophrenia.
Schizophrenia is associated with changes in the structure and functioning of a number of key brain systems, including prefrontal and medial temporal lobe regions involved in working memory and declarative memory, respectively. Imaging techniques provide an unparalleled window into these changes, allowing repeated assessments across pre- and post-onset stages of the disorder and in relation to c...
متن کاملThe validity of Psychosis Proneness Scales as vulnerability indicators in recent-onset schizophrenia patients.
The Psychosis Proneness Scales developed by the Chapmans and colleagues [Chapman, J.P., Chapman, L.J., Kwapil, T.R. Scales for the measurement of schizotypy. In: Raine., A., Lencz, T., Mednick, S.A., (Eds.). Schizotypal Personality. New York: Cambridge University Press, 1995. pp. 79-109] are widely used to identify non-patient individuals who are hypothesized to possess heightened vulnerability...
متن کاملOutcome of schizophrenia in relation to brain abnormalities.
This article reviews the 21 studies that investigated possible relationships between structural brain abnormalities and outcome in schizophrenia. Fifteen studies used computer tomography to visualize brain morphology. In these studies, images were obtained of the ventricles but not of specific brain regions. The remaining six studies used magnetic resonance imaging, examining possible relations...
متن کاملHypothalamic abnormalities in schizophrenia: sex effects and genetic vulnerability.
BACKGROUND This is a unique hypothalamic magnetic resonance imaging (MRI) study in schizophrenia, an important region in the limbic system. We hypothesized abnormal volumetric increases, with greater severity in multiplex families (more than one ill member) compared with simplex families (one ill). We tested the hypothesis that normal hypothalamic sexual dimorphism is disrupted in schizophrenia...
متن کاملInformation processing and attentional dysfunctions as vulnerability indicators in schizophrenia spectrum disorders.
The schizotypal personality disorder is believed to be part of the schizophrenic spectrum of disorders including schizophrenic patients as well as some of their seemingly unaffected relatives with discreet symptoms. Spectrum-individuals are characterised by a genetic vulnerability for schizophrenia. The vulnerability is connected with neurocognitive deficits independent of clinical state. Some ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Schizophrenia Bulletin
سال: 1994
ISSN: 0586-7614,1745-1701
DOI: 10.1093/schbul/20.1.89